Sex-related allergic rhinitis prevalence switch from childhood to adulthood: a systematic review and meta-analysis

M Pinart, T Keller, A Reich, M Fröhlich… - International archives of …, 2017 - karger.com
Background: A sex-related switch in the prevalence of asthma from childhood (male
predominance) to adulthood (female predominance) has been described, but for allergic …

[HTML][HTML] Is there a sex-shift in prevalence of allergic rhinitis and comorbid asthma from childhood to adulthood? A meta-analysis

M Fröhlich, M Pinart, T Keller, A Reich… - Clinical and translational …, 2017 - Springer
Background Allergic rhinitis and asthma as single entities affect more boys than girls in
childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift …

Current strategies for hemostatic control in acute trauma hemorrhage and trauma-induced coagulopathy

M Caspers, M Maegele, M Fröhlich - Expert review of hematology, 2018 - Taylor & Francis
Introduction: Despite advances in the treatment of severely injured patients that have
resulted in overall improved outcomes, uncontrolled hemorrhage still represents the most …

Selection and combination of acoustic features for the description of pathologic voices

D Michaelis, M Fröhlich, HW Strube - The Journal of the Acoustical …, 1998 - pubs.aip.org
The glottal to noise excitation ratio (GNE) is an acoustic measure designed to assess the
amount of noise in a pulse train generated by the oscillation of the vocal folds. So far its …

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking

U Renner, A Zeug, A Woehler, M Niebert… - Journal of cell …, 2012 - journals.biologists.com
Serotonin receptors 5-HT1A and 5-HT7 are highly coexpressed in brain regions implicated
in depression. However, their functional interaction has not been established. In the present …

Epidemiology and risk factors of multiple-organ failure after multiple trauma: an analysis of 31,154 patients from the TraumaRegister DGU

M Fröhlich, R Lefering, C Probst, T Paffrath… - Journal of Trauma …, 2014 - journals.lww.com
BACKGROUND In the severely injured who survive the early posttraumatic phase, multiple-
organ failure (MOF) is the main cause of morbidity and mortality. An enhanced prediction of …

Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart …

D Westermann, PM Becher, D Lindner… - Basic research in …, 2012 - Springer
Sildenafil inhibits cyclic GMP-specific phosphodiesterase type-5A (PDE5A) and can prevent
cardiac hypertrophy and left ventricular (LV) dysfunction in mice subjected to severe …

Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis

K Savvatis, I Müller, M Fröhlich, K Pappritz… - Basic research in …, 2014 - Springer
Increased levels of interleukin-6 (IL-6) have been observed in patients with acute
myocarditis and are associated with poor prognosis. This study was designed to examine …

[HTML][HTML] Which score should be used for posttraumatic multiple organ failure?-Comparison of the MODS, Denver-and SOFA-Scores

M Fröhlich, A Wafaisade, A Mansuri, P Koenen… - Scandinavian journal of …, 2016 - Springer
Background Multiple organ dysfunction and multiple organ failure (MOF) is still a major
complication and challenge in the treatment of severely injured patients. The incidence …

[HTML][HTML] Diversity in clinical management and protocols for the treatment of major bleeding trauma patients across European level I Trauma Centres

N Schäfer, A Driessen, M Fröhlich, EK Stürmer… - Scandinavian journal of …, 2015 - Springer
Background Uncontrolled haemorrhage is still the leading cause of preventable death after
trauma and the primary focus of any treatment strategy should be related to early detection …