Human and mouse NKG 2D ligands (NKG 2 DL s) are absent or only poorly expressed by
most normal cells but are upregulated by cell stress, hence, alerting the immune system in …

Abstract The human Major Histocompatibility Complex, known as the “Human Leukocyte
Antigen (HLA)”, could be defined as a “super locus”(historically called “supergene”) …

Antibodies (Abs) are the major component of the humoral immune response and a key
player in vaccination. The precise Ab-mediated inhibitory mechanisms leading to in vivo …

The drivers of critical coronavirus disease 2019 (COVID-19) remain unknown. Given major
confounding factors such as age and comorbidities, true mediators of this condition have …

Metastatic seeding is driven by cell-intrinsic and environmental cues, yet the contribution of
biomechanics is poorly known. We aim to elucidate the impact of blood flow on the arrest …

Patients with autosomal recessive (AR) IL-12p40 or IL-12Rβ1 deficiency display Mendelian
susceptibility to mycobacterial disease (MSMD) due to impaired IFN-γ production and, less …

Abstract Introduction COVID-19 long-haulers, also decribed as having “long-COVID” or post-
acute COVID-19 syndrome, represent 10% of COVID-19 patients and remain understudied …

HLA* LA implements a new graph alignment model for human leukocyte antigen (HLA) type
inference, based on the projection of linear alignments onto a variation graph. It enables …

The identity of histocompatibility loci, besides human leukocyte antigen (HLA), remains
elusive. The major histocompatibility complex (MHC) class I MICA gene is a candidate …

The Nck-associated protein 1–like (NCKAP1L) gene, alternatively called hematopoietic
protein 1 (HEM-1), encodes a hematopoietic lineage–specific regulator of the actin …