Objectives To analyse the impact of tumour necrosis factor inhibitors (TNFis) on spinal
radiographic progression in ankylosing spondylitis (AS). Methods Patients with AS in the …

Objectives To investigate whether the transient reduction in rheumatology services imposed
by virus containment measures during the COVID-19 pandemic was associated with …

Background Few studies have investigated the impact of obesity on the response to tumor
necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA). The aim of …

Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the
glucocorticoid receptor (GR). Dendritic cells (DCs), central actors for coordinating immune …

Abstract Introduction The Janus kinase (JAK) inhibitors tofacitinib and baricitinib are new
treatments for rheumatic diseases. Recent concerns regarding the risk of thrombosis have …

Background Sex differences with regard to clinical manifestations and response to tumor
necrosis factor inhibitors (TNFi) have been delineated for the radiographic form of axial …

Objective To compare effectiveness of treatment with secukinumab (SEC) with that of
alternative tumour necrosis factor inhibitors (TNFis) in patients with axial spondyloarthritis …

Background Genome-wide association studies have reported more than 100 risk loci for
rheumatoid arthritis (RA). These loci are shown to be enriched in immune cell-specific …

Objective To compare disease characteristics and outcomes between patients with axial
spondyloarthritis with non-radiographic disease (nr-axSpA), bilateral grade 2 sacroiliitis …

Objectives To integrate published single-cell RNA sequencing (scRNA-seq) data and
assess the contribution of synovial fibroblast (SF) subsets to synovial pathotypes and …