Independent relationship of left atrial size and mortality in patients with heart failure: an individual patient meta‐analysis of longitudinal data (MeRGE Heart Failure)

A Rossi, PL Temporelli, M Quintana… - European journal of …, 2009 - Wiley Online Library
Aims Left atrial (LA) size is considered a marker of poor prognosis in heart failure (HF)
patients. Prior studies have recruited relatively few subjects limiting their power to …

Age-dependent values of N-terminal pro-B-type natriuretic peptide are superior to a single cut-point for ruling out suspected systolic dysfunction in primary care

P Hildebrandt, PO Collinson, RN Doughty… - European heart …, 2010 - academic.oup.com
Aims The study evaluated the use of age-related decision limits for N-terminal pro-B-type
natriuretic peptide (NT-proBNP), for ruling out suspected systolic dysfunction in symptomatic …

Epidemiology of heart failure and ventricular dysfunction

N Sharpe, R Doughty - The Lancet, 1998 - thelancet.com
Admissions to hospital because of heart failure seem to be increasing, due partly to ageing
of populations and greater survival of patients with coronary heart disease. Substantial …

Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial

MJ Bolland, PA Barber, RN Doughty, B Mason… - Bmj, 2008 - bmj.com
Objective To determine the effect of calcium supplementation on myocardial infarction,
stroke, and sudden death in healthy postmenopausal women. Design Randomised, placebo …

Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease

RN Doughty, GA Whalley, G Gamble… - Journal of the American …, 1997 - jacc.org
Objectives. The aim of this study, a substudy of the Australia–New Zealand trial of carvedilol
in patients with heart failure due to ischemic heart disease, was to determine the effects of …

Effects of carvedilol on left ventricular remodeling after acute myocardial infarction: the CAPRICORN Echo Substudy

RN Doughty, GA Whalley, HA Walsh, GD Gamble… - Circulation, 2004 - Am Heart Assoc
Background—The CAPRICORN trial has shown that carvedilol improved outcome in
patients with left ventricular dysfunction after acute myocardial infarction treated with ACE …

Plasma N-terminal pro-brain natriuretic peptide and adrenomedullin: prognostic utility and prediction of benefit from carvedilol in chronic ischemic left ventricular …

AM Richards, R Doughty, MG Nicholls… - Journal of the American …, 2001 - jacc.org
OBJECTIVES We sought to assess plasma concentrations of the amino (N)-terminal portion
of pro-brain natriuretic peptide (N-BNP) and adrenomedullin for prediction of adverse …

Plasma amino-terminal pro-brain natriuretic peptide and accuracy of heart-failure diagnosis in primary care: a randomized, controlled trial

SP Wright, RN Doughty, A Pearl, GD Gamble… - Journal of the American …, 2003 - jacc.org
Objectives: The purpose of this study was to determine the effect of amino-terminal pro-brain
natriuretic peptide (N-BNP) on the diagnostic accuracy of heart failure (HF) in primary care …

Physician-directed patient self-management of left atrial pressure in advanced chronic heart failure

J Ritzema, R Troughton, I Melton, I Crozier, R Doughty… - Circulation, 2010 - Am Heart Assoc
Background—Previous studies suggest that management of ambulatory hemodynamics
may improve outcomes in chronic heart failure. We conducted a prospective, observational …

Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial

JA Ezekowitz, E Colin-Ramirez, H Ross, J Escobedo… - The Lancet, 2022 - thelancet.com
Background Dietary restriction of sodium has been suggested to prevent fluid overload and
adverse outcomes for patients with heart failure. We designed the Study of Dietary …