User profiles for "author:Samuel Bitoun"
Samuel BitounRheumatology departement, Bicêtre Hospital, Paris Saclay University Verified email at aphp.fr Cited by 412 |
Rituximab impairs B cell response but not T cell response to COVID‐19 vaccine in autoimmune diseases
S Bitoun, J Henry, D Desjardins… - Arthritis & …, 2022 - Wiley Online Library
Objective Antibody response to the messenger RNA (mRNA) COVID‐19 vaccine has been
shown to be diminished in rituximab (RTX)–treated patients. We undertook this study to …
shown to be diminished in rituximab (RTX)–treated patients. We undertook this study to …
[PDF][PDF] Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease
DE Matei, M Menon, DG Alber, AM Smith… - Med, 2021 - cell.com
Background Evidence suggests an important role for gut-microbiota dysbiosis in the
development of rheumatoid arthritis (RA). The link between changes in gut bacteria and the …
development of rheumatoid arthritis (RA). The link between changes in gut bacteria and the …
Treatment of neurosarcoidosis: a comparative study of methotrexate and mycophenolate mofetil
Objective: To compare the efficacy of methotrexate (MTX) and mycophenolate mofetil (MMF)
in the prevention of relapses in neurosarcoidosis. Methods: We conducted a retrospective …
in the prevention of relapses in neurosarcoidosis. Methods: We conducted a retrospective …
Melatonin treatment protects liver of Zucker rats after ischemia/reperfusion by diminishing oxidative stress and apoptosis
R Kireev, S Bitoun, S Cuesta, A Tejerina… - European Journal of …, 2013 - Elsevier
Fatty livers occur in up to 20% of potential liver donors and increase cellular injury during the
ischemia/reperfusion phase, so any intervention that could enable a better outcome of grafts …
ischemia/reperfusion phase, so any intervention that could enable a better outcome of grafts …
[HTML][HTML] Response to COVID-19 mRNA vaccination in multiple myeloma is conserved but impaired compared to controls
S Bitoun, J Henry, C Vauloup-Fellous, N Dib… - Journal of Hematology & …, 2021 - Springer
Patients with multiple myeloma are at high risk of severe forms of COVID-19. Despite data
showing diminished response to vaccine, the era of highly efficient mRNA vaccine might be …
showing diminished response to vaccine, the era of highly efficient mRNA vaccine might be …
Methotrexate and BAFF interaction prevents immunization against TNF inhibitors
S Bitoun, G Nocturne, B Ly, R Krzysiek… - Annals of the …, 2018 - ard.bmj.com
Objectives TNF inhibitors (TNFi) can induce anti-drug antibodies (ADA) in patients with
autoimmune diseases (AID) leading to clinical resistance. We explored a new way of using …
autoimmune diseases (AID) leading to clinical resistance. We explored a new way of using …
Response to biologic drugs in patients with rheumatoid arthritis and antidrug antibodies
Importance There are conflicting data on the association of antidrug antibodies with
response to biologic disease–modifying antirheumatic drugs (bDMARDs) in rheumatoid …
response to biologic disease–modifying antirheumatic drugs (bDMARDs) in rheumatoid …
[HTML][HTML] Characterization of phenotypes and functional activities of leukocytes from rheumatoid arthritis patients by mass cytometry
A Leite Pereira, S Bitoun, A Paoletti… - Frontiers in …, 2019 - frontiersin.org
Background: Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease
and leads to persistent chronic inflammation. The pathophysiology of the disease is …
and leads to persistent chronic inflammation. The pathophysiology of the disease is …
[HTML][HTML] Pegylation reduces the uptake of certolizumab pegol by dendritic cells and epitope presentation to T-cells
M de Bourayne, S Meunier, S Bitoun, E Correia… - Frontiers in …, 2022 - frontiersin.org
Pegylation of biopharmaceuticals is the most common strategy to increase their half-life in
the blood and is associated with a reduced immunogenicity. As antigen presentation is a …
the blood and is associated with a reduced immunogenicity. As antigen presentation is a …
Prophylaxis with tixagevimab/cilgavimab is associated with lower COVID-19 incidence and severity in patients with autoimmune diseases
M Thomas, M Masson, S Bitoun, S Hamroun… - …, 2023 - academic.oup.com
Objective To describe the clinical efficacy of tixagevimab/cilgavimab in pre-exposure
prophylaxis in patients at risk of severe coronavirus disease 2019 (COVID-19) and …
prophylaxis in patients at risk of severe coronavirus disease 2019 (COVID-19) and …