User profiles for "author:Thomas Schwartz"

Thomas U. Schwartz

Professor of Biology
Verified email at mit.edu
Cited by 8202

Tackling antibiotic resistance: the environmental framework

TU Berendonk, CM Manaia, C Merlin… - Nature reviews …, 2015 - nature.com
Antibiotic resistance is a threat to human and animal health worldwide, and key measures
are required to reduce the risks posed by antibiotic resistance genes that occur in the …

[PDF][PDF] The nuclear pore complex as a flexible and dynamic gate

KE Knockenhauer, TU Schwartz - Cell, 2016 - cell.com
Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary
transport gates for molecular exchange between nucleus and cytoplasm. Stripping the …

[HTML][HTML] Glutamate neurocircuitry: theoretical underpinnings in schizophrenia

TL Schwartz, S Sachdeva, SM Stahl - Frontiers in pharmacology, 2012 - frontiersin.org
The Dopamine Hypothesis of Schizophrenia is actively being challenged by the NMDA
Receptor Hypofunctioning Hypothesis of Schizophrenia. The latter hypothesis may actually …

Congressional oversight overlooked: Police patrols versus fire alarms

MD McCubbins, T Schwartz - American journal of political science, 1984 - JSTOR
Scholars have often remarked that Congress neglects its oversight responsibility. We argue
that Congress does no such thing: what appears to be a neglect of oversight really is the …

Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms

T Schwartz, W Kohnen, B Jansen… - FEMS microbiology …, 2003 - academic.oup.com
In view of the increasing interest in the possible role played by hospital and municipal
wastewater systems in the selection of antibiotic-resistant bacteria, biofilms were …

[HTML][HTML] Antibiotic residues in final effluents of European wastewater treatment plants and their impact on the aquatic environment

S Rodriguez-Mozaz, I Vaz-Moreira… - Environment …, 2020 - Elsevier
A comprehensive monitoring of a broad set of antibiotics in the final effluent of wastewater
treatment plants (WWTPs) of 7 European countries (Portugal, Spain, Ireland, Cyprus …

A general amphipathic α-helical motif for sensing membrane curvature

G Drin, JF Casella, R Gautier, T Boehmer… - Nature structural & …, 2007 - nature.com
Abstract The Golgi-associated protein ArfGAP1 has an unusual membrane-adsorbing
amphipathic α-helix: its polar face is weakly charged, containing mainly serine and …

Antibiotic resistance in European wastewater treatment plants mirrors the pattern of clinical antibiotic resistance prevalence

KMM Pärnänen, C Narciso-da-Rocha, D Kneis… - Science …, 2019 - science.org
Integrated antibiotic resistance (AR) surveillance is one of the objectives of the World Health
Organization global action plan on antimicrobial resistance. Urban wastewater treatment …

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

RA Saxton, KE Knockenhauer, RL Wolfson… - Science, 2016 - science.org
Eukaryotic cells coordinate growth with the availability of nutrients through the mechanistic
target of rapamycin complex 1 (mTORC1), a master growth regulator. Leucine is of particular …

[BOOK][B] The logic of collective choice

T Schwartz - 1986 - degruyter.com
This book issued from my reflections on the Marquis de Condorcet's Paradox of Voting and
Kenneth Arrow's Impossibility Theorem. Its germ was my Notes on the Abstract Theory of …