Resveratrol, a naturally occurring compound of various fruits such as grapes, is thought to
possess chemopreventive properties. The levels of resveratrol in grapes and grape products …

B lymphocytes contribute to immunity through production of antibodies, antigen presentation
to T cells, and secretion of cytokines. B cells are generally considered in autoimmune …

B lymphocytes have critical roles as positive and negative regulators of immunity. Their
inhibitory function has been associated primarily with interleukin 10 (IL-10) because B-cell …

Background Dialysis and kidney transplant patients are vulnerable populations for COVID-
19 related disease and mortality. Methods We conducted a prospective study exploring the …

Th17 cells provide protection at barrier tissues but may also contribute to immune pathology.
The relevance and induction mechanisms of pathologic Th17 responses in humans are …

The myeloid differentiation primary response gene 88 (Myd88) is critical for protection
against pathogens. However, we demonstrate here that MyD88 expression in B cells inhibits …

Here, we report an update of the VDJdb database with a substantial increase in the number
of T-cell receptor (TCR) sequences and their cognate antigens. The update further provides …

FOXP3+ regulatory T cells (Tregs) maintain tolerance against self-antigens and innocuous
environmental antigens. However, it is still unknown whether Treg-mediated tolerance is …

T cell immunity toward SARS-CoV-2 spike (S-), membrane (M-), and nucleocapsid (N-)
proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T …

B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious,
autoimmune, and malignant diseases. Here, we have identified a natural plasma cell subset …