Background: Osteoarthritis of the knee affects up to 10% of the elderly population. The
condition is frequently treated by intra-articular injection of hyaluronic acid. We performed a …

CONTEXT: High-intensity focussed ultrasound (HIFU) is an emerging minimally invasive
treatment option for prostate cancer. OBJECTIVE: Our aim was to assess the efficacy and safety …

Cervical total disc replacement (CTDR) has been increasingly used as an alternative to
fusion surgery in patients with pain or neurological symptoms in the cervical spine who do not …

Objectives: A new decision-making process was set up by the Austrian Ministry of Health to
regulate coverage of new proposed Extra Medical Services (EMS; German: Medizinische …

Despite the large availability of diagnostic tests and procedures and their importance to
medicine, evidence for their appropriate use is often limited. Unfortunately, the evaluation of tests …

Die randomisiert kontrollierte Studie (engl. Randomised Controlled Trial, RCT) steht in der
Hierarchie der Evidenz an der obersten Stufe aller Primärstudien, sie ist heute der …

Nowadays the Randomised Controlled Trial (RCT) is seen as the gold standard for estimating
the effectiveness of an observed intervention, achieving the highest hierarchy of evidence …

Over the past years, systematic reviews and meta-analyses have led to significant changes
in clinical medicine and health policy. To date, they can be viewed as the most objective …

Systematische Übersichtsarbeiten und Meta-Analysen haben in den letzten Jahren zu
wesentlichen Veränderungen in der klinischen Medizin und der Gesundheitspolitik geführt. Sie …

… China), the prognosis for mad honey intoxication is very good, … Although fatalities are very
rare, mad honey ingestion may … to honey, mad honey and its uses, the effects of mad honey …